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Calprotectin

Seeing diarrhea, reduced performance, increased variability, or suspected gut inflammation in pigs or poultry? Fecal calprotectin analysis provides a quantitative assessment of host-derived inflammation markers, offering direct insight into intestinal integrity, immune activation, and gut health status.

Where it helps?

  • In production animals, fecal calprotectin levels help link gut inflammation to performance losses (ADG, FCR, uniformity, mortality risk).
  • Detects intestinal inflammation and epithelial stress, often associated with pathogen challenge, dysbiosis, or dietary imbalance.
  • Provides evidence for gut health interventions (e.g., feed additives, vaccines, management strategies) targeting inflammation control.
  • For feed additive companies, calprotectin provides a strong, host-response-based endpoint demonstrating reduced inflammation and improved gut resilience.

How does it work?

Calprotectin is a host-derived protein released by neutrophils or heterophils during inflammation and can be quantified in feces as a non-invasive marker of intestinal immune activation.

We typically analyze feces, but intestinal samples (digesta/mucosa) can also be used in controlled studies.

  • Feces: ideal for non-invasive sampling.
  • Digesta: used in research settings for deeper mechanistic insight.

Our BioFreeze™ kits ensure stable preservation of host proteins and smooth logistics.

What do we measure?

  • Calprotectin – a calcium-binding protein complex (S100A8/S100A9) released during inflammatory cell activation; widely used as a marker of intestinal inflammation and mucosal damage.

Typical use cases

  • Challenge trials: quantify inflammatory response to pathogens or stressors.
  • Additive validation: demonstrate anti-inflammatory effects and improved gut resilience.
  • Diet formulation studies: assess impact of ingredients on gut integrity.

Sample types

  • Feces
  • Digesta

How to Order

  1. Contact us either by email diagnostics@alimetrics.com or alternatively use the contact form below.
  2. Indicate your interest in the BioFreeze™ sample collection solution, one or more of our unique gut health panels or a customized selection of analyses.
  3. We can help you plan a solution best suited to your needs.
  4. We will provide you with a quotation and further instructions within two business days.

Request Service

Use this form to request information of our analysis services. We’ll get back to you within two business days.

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